The dominant negative effect of thyroid hormone receptor splicing variant alpha 2 does not require binding to a thyroid response element.

Liu, R T; Suzuki, S; Miyamoto, T; Takeda, T; Ozata, M; DeGroot, L J

Liu, R T; Suzuki, S; Miyamoto, T; Takeda, T; Ozata, M; DeGroot, L J.

Affiliation

Liu RT; Department of Medicine, University of Chicago, Illinois 60637, USA.

Mol Endocrinol ; 9(1): 86-95, 1995 Jan.

Article in En | MEDLINE | ID: mdl-7760853

Subject(s)

Gene Expression Regulation/drug effects; RNA Splicing; Receptors, Thyroid Hormone/physiology; Regulatory Sequences, Nucleic Acid; Transcriptional Activation/drug effects; Animals; Base Sequence; Carcinoma, Hepatocellular/pathology; Cell Line, Transformed; Chlorocebus aethiops; DNA/genetics; DNA/metabolism; Depression, Chemical; Humans; Liver Neoplasms/pathology; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Binding; Receptors, Thyroid Hormone/genetics; Recombinant Fusion Proteins/pharmacology; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Receptors, Thyroid Hormone / Transcriptional Activation / Regulatory Sequences, Nucleic Acid / RNA Splicing / Gene Expression Regulation Limits: Animals / Humans Language: En Journal: Mol Endocrinol Journal subject: BIOLOGIA MOLECULAR / ENDOCRINOLOGIA Year: 1995 Type: Article Affiliation country: United States

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