Large-scale preparation and biochemical characterization of a new high purity factor IX concentrate prepared by metal chelate affinity chromatography.

Feldman, P A; Bradbury, P I; Williams, J D; Sims, G E; McPhee, J W; Pinnell, M A; Harris, L; Crombie, G I; Evans, D R

Feldman, P A; Bradbury, P I; Williams, J D; Sims, G E; McPhee, J W; Pinnell, M A; Harris, L; Crombie, G I; Evans, D R.

Affiliation

Feldman PA; Bio Products Laboratory, Elstree, Hertfordshire, UK.

Blood Coagul Fibrinolysis ; 5(6): 939-48, 1994 Dec.

Article in En | MEDLINE | ID: mdl-7893930

Subject(s)

Chelating Agents; Chromatography, Affinity/methods; Copper; Factor IX/isolation & purification; Chromatography, High Pressure Liquid; Drug Stability; Electrophoresis, Polyacrylamide Gel; Factor IX/chemistry; Factor IX/metabolism; Factor IXa/analysis; Freeze Drying; Humans; Molecular Weight

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Collection: 01-internacional Database: MEDLINE Main subject: Factor IX / Chelating Agents / Chromatography, Affinity / Copper Limits: Humans Language: En Journal: Blood Coagul Fibrinolysis Journal subject: ANGIOLOGIA / HEMATOLOGIA Year: 1994 Type: Article Affiliation country: United kingdom

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