Increases of intracellular magnesium promote glycodeoxycholate-induced apoptosis in rat hepatocytes.

Patel, T; Bronk, S F; Gores, G J

Patel, T; Bronk, S F; Gores, G J.

Affiliation

Patel T; Center for Basic Research in Digestive Diseases, Mayo Clinic, Rochester, Minnesota 55905.

J Clin Invest ; 94(6): 2183-92, 1994 Dec.

Article in En | MEDLINE | ID: mdl-7989573

Subject(s)

Apoptosis/drug effects; Glycodeoxycholic Acid/pharmacology; Liver/drug effects; Magnesium/metabolism; Animals; Bile Acids and Salts/pharmacology; Cations, Divalent/metabolism; Cell Nucleus/pathology; Cells, Cultured; Cytosol/metabolism; Dose-Response Relationship, Drug; Endonucleases/metabolism; Hydrogen-Ion Concentration; Liver/cytology; Liver/pathology; Male; Microscopy, Electron; Rats; Rats, Sprague-Dawley; Signal Transduction

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Apoptosis / Glycodeoxycholic Acid / Liver / Magnesium Limits: Animals Language: En Journal: J Clin Invest Year: 1994 Type: Article

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