Effect of cryoprotectants on freezing, lyophilization, and storage of lyophilized recombinant alpha 1-antitrypsin formulations.

Vemuri, S; Yu, C D; Roosdorp, N

Vemuri, S; Yu, C D; Roosdorp, N.

Affiliation

Vemuri S; Scios Nova, Mountain View, California 94043.

PDA J Pharm Sci Technol ; 48(5): 241-6, 1994.

Article in En | MEDLINE | ID: mdl-8000898

Subject(s)

Cryopreservation/methods; Cryoprotective Agents/chemistry; Drug Storage/methods; Freeze Drying/methods; alpha 1-Antitrypsin/chemistry; Buffers; Chemistry, Pharmaceutical; Drug Packaging; Drug Stability; Enzyme-Linked Immunosorbent Assay; Hydrogen-Ion Concentration; Lactose/chemistry; Povidone/chemistry; Proteins/analysis; Recombinant Proteins/chemistry; Sucrose/chemistry

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Collection: 01-internacional Database: MEDLINE Main subject: Cryopreservation / Alpha 1-Antitrypsin / Cryoprotective Agents / Drug Storage / Freeze Drying Language: En Journal: PDA J Pharm Sci Technol Journal subject: FARMACIA / FARMACOLOGIA Year: 1994 Type: Article

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