Specific inhibition of pre-ribosomal RNA processing in extracts from the lymphosarcoma cells treated with 5-fluorouracil.

Ghoshal, K; Jacob, S T

Ghoshal, K; Jacob, S T.

Affiliation

Ghoshal K; Department of Pharmacology and Molecular Biology, Chicago Medical School, North Chicago, Illinois 60064.

Cancer Res ; 54(3): 632-6, 1994 Feb 01.

Article in En | MEDLINE | ID: mdl-8306322

Subject(s)

Fluorouracil/pharmacology; Lymphoma, Non-Hodgkin/drug therapy; Lymphoma, Non-Hodgkin/genetics; RNA Precursors/drug effects; RNA Precursors/genetics; RNA, Ribosomal/drug effects; RNA, Ribosomal/genetics; Animals; Base Sequence; Cell Division/drug effects; Cell Division/physiology; Cell Nucleus/chemistry; Cell Nucleus/drug effects; Cell Nucleus/physiology; DNA, Ribosomal/drug effects; DNA, Ribosomal/genetics; Fluorouracil/metabolism; Lymphoma, Non-Hodgkin/metabolism; Mice; Molecular Sequence Data; RNA Precursors/physiology; RNA, Neoplasm/metabolism; RNA, Ribosomal/physiology; Trans-Activators/biosynthesis; Transcription, Genetic/drug effects; Tumor Cells, Cultured/drug effects; Uracil Nucleotides/metabolism; Uracil Nucleotides/pharmacology; Uridine Triphosphate/analogs & derivatives; Uridine Triphosphate/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Lymphoma, Non-Hodgkin / RNA, Ribosomal / RNA Precursors / Fluorouracil Limits: Animals Language: En Journal: Cancer Res Year: 1994 Type: Article

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