Molecular epidemiology of aflatoxin exposures: validation of aflatoxin-N7-guanine levels in urine as a biomarker in experimental rat models and humans.

Groopman, J D; Wild, C P; Hasler, J; Junshi, C; Wogan, G N; Kensler, T W

Groopman, J D; Wild, C P; Hasler, J; Junshi, C; Wogan, G N; Kensler, T W.

Affiliation

Groopman JD; Department of Environmental Health Sciences, School of Hygiene and Public Health, Johns Hopkins University, Baltimore, MD 21205.

Environ Health Perspect ; 99: 107-13, 1993 Mar.

Article in En | MEDLINE | ID: mdl-8319607

Subject(s)

Aflatoxins/adverse effects; DNA Adducts; Guanine/urine; Liver Neoplasms/etiology; Adolescent; Adult; Aflatoxin B1/urine; Aflatoxins/administration & dosage; Aflatoxins/urine; Animals; Biomarkers/urine; China; DNA/urine; DNA Damage; Female; Gambia; Humans; Liver Neoplasms, Experimental/chemically induced; Liver Neoplasms, Experimental/urine; Male; Middle Aged; Rats; Rats, Inbred F344

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: DNA Adducts / Aflatoxins / Guanine / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies / Screening_studies Limits: Adolescent / Adult / Animals / Female / Humans / Male / Middle aged Country/Region as subject: Africa / Asia Language: En Journal: Environ Health Perspect Year: 1993 Type: Article

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