WAY100135: a novel, selective antagonist at presynaptic and postsynaptic 5-HT1A receptors.

Fletcher, A; Bill, D J; Bill, S J; Cliffe, I A; Dover, G M; Forster, E A; Haskins, J T; Jones, D; Mansell, H L; Reilly, Y

Fletcher, A; Bill, D J; Bill, S J; Cliffe, I A; Dover, G M; Forster, E A; Haskins, J T; Jones, D; Mansell, H L; Reilly, Y.

Affiliation

Fletcher A; Department of Biomedical Research, Wyeth Research Ltd., Berkshire, UK.

Eur J Pharmacol ; 237(2-3): 283-91, 1993 Jun 24.

Article in En | MEDLINE | ID: mdl-8365456

Subject(s)

Piperazines/pharmacology; Serotonin Antagonists; 8-Hydroxy-2-(di-n-propylamino)tetralin/antagonists & inhibitors; Animals; Behavior, Animal/drug effects; Electrophysiology; Female; Guinea Pigs; Hippocampus/drug effects; Hippocampus/metabolism; Hypothermia/chemically induced; Hypothermia/drug therapy; Ileum/drug effects; Male; Mice; Piperazines/administration & dosage; Piperazines/therapeutic use; Radioligand Assay; Raphe Nuclei/drug effects; Rats; Rats, Sprague-Dawley; Receptors, Serotonin/metabolism; Serotonin/analogs & derivatives; Serotonin/pharmacology; Stereoisomerism

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Serotonin Antagonists Limits: Animals Language: En Journal: Eur J Pharmacol Year: 1993 Type: Article Affiliation country: United kingdom

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