Sequence variability of the glycoprotein gene of bovine respiratory syncytial virus.
J Gen Virol
; 74 ( Pt 9): 2001-4, 1993 Sep.
Article
in En
| MEDLINE
| ID: mdl-8376974
ABSTRACT
Sequence variation in the attachment glycoprotein G of bovine respiratory syncytial virus (BRSV) was determined. The nucleotide sequences of the G mRNAs of the A51908, VC464 and FS-1 strains of BRSV were compared with the published sequence of the BRSV strain 391-2. Nucleotide sequence alignment showed that overall they are highly conserved, with 90 to 97% identity. In addition, the coding region of strain A51908 was longer by 18 nucleotides at the 3' end. An 84 to 95% level of identity was observed among the deduced amino acid sequences of the G proteins of BRSV strains. A maximum divergence of 19% was found when the extracellular domains of the G proteins were compared. The level of diversity would be consistent, by analogy to the human respiratory syncytial viruses, with these BRSV strains forming a single subgroup.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
Respiratory Syncytial Viruses
/
Genetic Variation
/
Viral Proteins
/
HN Protein
/
Genes, Viral
Limits:
Animals
Language:
En
Journal:
J Gen Virol
Year:
1993
Type:
Article