Biodistribution in tumour-bearing mice of polycationic, amphoteric and polyanionic branched polypeptides with a poly(L-lysine) backbone labelled with 125I and 111In: tumour accumulation less than that of labelled serum proteins.

Pimm, M V; Hudecz, F

Pimm, M V; Hudecz, F.

Affiliation

Pimm MV; Cancer Research Laboratories, University of Nottingham, UK.

J Cancer Res Clin Oncol ; 122(1): 45-54, 1996.

Article in En | MEDLINE | ID: mdl-8543592

Subject(s)

Blood Proteins/pharmacokinetics; Mammary Neoplasms, Experimental/metabolism; Melanoma, Experimental/metabolism; Polylysine/pharmacokinetics; Animals; Cell Membrane Permeability; Chromatography, Gel; Female; Indium Radioisotopes/pharmacokinetics; Iodine Radioisotopes/pharmacokinetics; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Neoplasm Transplantation; Polylysine/analogs & derivatives; Tissue Distribution

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Collection: 01-internacional Database: MEDLINE Main subject: Polylysine / Melanoma, Experimental / Blood Proteins / Mammary Neoplasms, Experimental Limits: Animals Language: En Journal: J Cancer Res Clin Oncol Year: 1996 Type: Article Affiliation country: United kingdom

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