Alpha interferon suppresses the cyclin D3 and cdc25A genes, leading to a reversible G0-like arrest.

Tiefenbrun, N; Melamed, D; Levy, N; Resnitzky, D; Hoffman, I; Reed, S I; Kimchi, A

Tiefenbrun, N; Melamed, D; Levy, N; Resnitzky, D; Hoffman, I; Reed, S I; Kimchi, A.

Affiliation

Tiefenbrun N; Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot, Israel.

Mol Cell Biol ; 16(7): 3934-44, 1996 Jul.

Article in En | MEDLINE | ID: mdl-8668211

Subject(s)

Cell Cycle Proteins/biosynthesis; Cell Cycle/drug effects; Cyclins/biosynthesis; Gene Expression Regulation, Neoplastic/drug effects; Interferon-alpha/pharmacology; Phosphoprotein Phosphatases/biosynthesis; Burkitt Lymphoma; Cell Cycle Proteins/metabolism; Cell Division/drug effects; Cell Line; Cyclin D3; Cyclin-Dependent Kinases/metabolism; Cyclins/isolation & purification; GTP-Binding Proteins/biosynthesis; Humans; Kinetics; Phosphoprotein Phosphatases/metabolism; Resting Phase, Cell Cycle; Suppression, Genetic; Tetradecanoylphorbol Acetate/pharmacology; Time Factors; Tumor Cells, Cultured; cdc25 Phosphatases

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Cell Cycle / Interferon-alpha / Cyclins / Phosphoprotein Phosphatases / Cell Cycle Proteins Limits: Humans Language: En Journal: Mol Cell Biol Year: 1996 Type: Article Affiliation country: Israel

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