Thapsigargin induces rapid, transient growth inhibition and c-fos expression followed by sustained growth stimulation in mouse keratinocyte cultures.

Harmon, C S; Ducote, J; Xiong, Y

Harmon, C S; Ducote, J; Xiong, Y.

Affiliation

Harmon CS; Preclinical Dermatology Research, Hoffmann-La Roche Inc., Nutley, New Jersey, U.S.A.

J Invest Dermatol ; 107(2): 188-94, 1996 Aug.

Article in En | MEDLINE | ID: mdl-8757761

Subject(s)

Keratinocytes/drug effects; Proto-Oncogene Proteins c-fos/metabolism; Thapsigargin/pharmacology; Animals; Calcium/metabolism; Calcium-Transporting ATPases/antagonists & inhibitors; Cell Division/drug effects; Cell Survival/drug effects; Indoles/pharmacology; Intracellular Membranes/metabolism; Keratinocytes/cytology; Keratinocytes/metabolism; Maleimides/pharmacology; Mice; Protein Kinase C/antagonists & inhibitors; Protein Synthesis Inhibitors/pharmacology; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Keratinocytes / Proto-Oncogene Proteins c-fos / Thapsigargin Limits: Animals Language: En Journal: J Invest Dermatol Year: 1996 Type: Article Affiliation country: United States

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