Electrophysiological, biochemical, neurohormonal and behavioural studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist.

Fletcher, A; Forster, E A; Bill, D J; Brown, G; Cliffe, I A; Hartley, J E; Jones, D E; McLenachan, A; Stanhope, K J; Critchley, D J; Childs, K J; Middlefell, V C; Lanfumey, L; Corradetti, R; Laporte, A M; Gozlan, H; Hamon, M; Dourish, C T

Fletcher, A; Forster, E A; Bill, D J; Brown, G; Cliffe, I A; Hartley, J E; Jones, D E; McLenachan, A; Stanhope, K J; Critchley, D J; Childs, K J; Middlefell, V C; Lanfumey, L; Corradetti, R; Laporte, A M; Gozlan, H; Hamon, M; Dourish, C T.

Affiliation

Fletcher A; Department of Neuropharmacology, Wyeth Research, Ltd., Maidenhead, Berkshire, UK.

Behav Brain Res ; 73(1-2): 337-53, 1996.

Article in En | MEDLINE | ID: mdl-8788530

Subject(s)

Behavior, Animal/drug effects; Brain Chemistry/drug effects; Neurotransmitter Agents/metabolism; Piperazines/pharmacology; Pyridines/pharmacology; Serotonin Antagonists/pharmacology; Adrenocorticotropic Hormone/blood; Animals; Cognition/drug effects; Electrophysiology; Female; Hippocampus/cytology; Hippocampus/drug effects; Hyperphagia/chemically induced; Hypothermia, Induced; Male; Mice; Pyramidal Cells/drug effects; Raphe Nuclei/drug effects; Rats; Rats, Sprague-Dawley

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Collection: 01-internacional Database: MEDLINE Main subject: Piperazines / Pyridines / Serotonin Antagonists / Behavior, Animal / Brain Chemistry / Neurotransmitter Agents Limits: Animals Language: En Journal: Behav Brain Res Year: 1996 Type: Article Affiliation country: United kingdom

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