The antiproliferative effect of 8-chloro-adenosine, an active metabolite of 8-chloro-cyclic adenosine monophosphate, and disturbances in nucleic acid synthesis and cell cycle kinetics.

Langeveld, C H; Jongenelen, C A; Theeuwes, J W; Baak, J P; Heimans, J J; Stoof, J C; Peters, G J

Langeveld, C H; Jongenelen, C A; Theeuwes, J W; Baak, J P; Heimans, J J; Stoof, J C; Peters, G J.

Affiliation

Langeveld CH; Department of Neurology, Graduate School of Neurosciences Amsterdam, Vrije Universiteit, The Netherlands.

Biochem Pharmacol ; 53(2): 141-8, 1997 Jan 24.

Article in En | MEDLINE | ID: mdl-9037246

Subject(s)

2-Chloroadenosine/analogs & derivatives; Antineoplastic Agents/pharmacology; DNA/biosynthesis; RNA/biosynthesis; 2-Chloroadenosine/metabolism; 2-Chloroadenosine/pharmacology; 8-Bromo Cyclic Adenosine Monophosphate/analogs & derivatives; 8-Bromo Cyclic Adenosine Monophosphate/pharmacology; Cell Cycle/drug effects; Cell Division/drug effects; Flow Cytometry; Humans; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: DNA / RNA / 2-Chloroadenosine / Antineoplastic Agents Limits: Humans Language: En Journal: Biochem Pharmacol Year: 1997 Type: Article Affiliation country: Netherlands

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