Interleukin-1beta is differentially expressed by human dermal papilla cells in response to PKC activation and is a potent inhibitor of human hair follicle growth in organ culture.

Xiong, Y; Harmon, C S

Xiong, Y; Harmon, C S.

Affiliation

Xiong Y; Preclinical Dermatology Research, Hoffmann-La Roche, Nutley, NJ 07110, USA.

J Interferon Cytokine Res ; 17(3): 151-7, 1997 Mar.

Article in En | MEDLINE | ID: mdl-9085940

Subject(s)

Growth Inhibitors/biosynthesis; Hair Follicle/drug effects; Interleukin-1/biosynthesis; Protein Kinase C/drug effects; Skin/drug effects; Tetradecanoylphorbol Acetate/pharmacology; Cells, Cultured; Enzyme Activation; Enzyme Inhibitors/pharmacology; Growth Inhibitors/metabolism; Hair Follicle/growth & development; Hair Follicle/metabolism; Humans; Indoles/pharmacology; Interleukin-1/metabolism; Maleimides/pharmacology; Organ Culture Techniques; Skin/cytology; Skin/metabolism; Tetradecanoylphorbol Acetate/antagonists & inhibitors

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Collection: 01-internacional Database: MEDLINE Main subject: Skin / Protein Kinase C / Tetradecanoylphorbol Acetate / Interleukin-1 / Hair Follicle / Growth Inhibitors Limits: Humans Language: En Journal: J Interferon Cytokine Res Journal subject: ALERGIA E IMUNOLOGIA Year: 1997 Type: Article Affiliation country: United States

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