High-level expression of the retinoic acid receptor beta gene in normal cells of the uterine cervix is regulated by the retinoic acid receptor alpha and is abnormally down-regulated in cervical carcinoma cells.

Geisen, C; Denk, C; Gremm, B; Baust, C; Karger, A; Bollag, W; Schwarz, E

Geisen, C; Denk, C; Gremm, B; Baust, C; Karger, A; Bollag, W; Schwarz, E.

Affiliation

Geisen C; German Cancer Research Center, Heidelberg.

Cancer Res ; 57(8): 1460-7, 1997 Apr 15.

Article in En | MEDLINE | ID: mdl-9108446

Subject(s)

Cervix Uteri/metabolism; Gene Expression Regulation, Neoplastic; Receptors, Retinoic Acid/genetics; Receptors, Retinoic Acid/physiology; Uterine Cervical Neoplasms/genetics; Blotting, Northern; Down-Regulation; Epithelium/metabolism; Female; HeLa Cells; Humans; Hybrid Cells/metabolism; Keratinocytes/metabolism; RNA, Messenger/metabolism; Uterine Cervical Neoplasms/metabolism

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Collection: 01-internacional Database: MEDLINE Main subject: Gene Expression Regulation, Neoplastic / Uterine Cervical Neoplasms / Cervix Uteri / Receptors, Retinoic Acid Limits: Female / Humans Language: En Journal: Cancer Res Year: 1997 Type: Article

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