Topoisomerase II inhibitors induce cleavage of nuclear and 35-kb plastid DNAs in the malarial parasite Plasmodium falciparum.

Weissig, V; Vetro-Widenhouse, T S; Rowe, T C

Weissig, V; Vetro-Widenhouse, T S; Rowe, T C.

Affiliation

Weissig V; Department of Pharmacology and Therapeutics, University of Florida College of Medicine, Gainesville 32610-0267, USA.

DNA Cell Biol ; 16(12): 1483-92, 1997 Dec.

Article in En | MEDLINE | ID: mdl-9428797

Subject(s)

Ciprofloxacin/pharmacology; Etoposide/pharmacology; Plasmodium falciparum/genetics; Topoisomerase II Inhibitors; Animals; DNA Topoisomerases, Type II/metabolism; DNA, Circular/drug effects; DNA, Circular/metabolism; DNA, Protozoan/drug effects; DNA, Protozoan/metabolism; Enzyme Inhibitors/pharmacology; Exonucleases/metabolism; Hot Temperature; Plasmodium falciparum/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Plasmodium falciparum / Ciprofloxacin / Etoposide / Topoisomerase II Inhibitors Limits: Animals Language: En Journal: DNA Cell Biol Journal subject: BIOLOGIA MOLECULAR Year: 1997 Type: Article Affiliation country: United States

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