Exonuclease enhances hybridization efficiency: improved direct cycle sequencing and point mutation detection.

Somers, V A; Leimbach, D A; Murtagh, J J; Thunnissen, F B

Somers, V A; Leimbach, D A; Murtagh, J J; Thunnissen, F B.

Affiliation

Somers VA; Department of Pathology, Maastricht University, The Netherlands. vso@lpat.azm.nl

Biochim Biophys Acta ; 1379(1): 42-52, 1998 Jan 08.

Article in En | MEDLINE | ID: mdl-9468331

Subject(s)

Exodeoxyribonucleases/metabolism; Nucleic Acid Hybridization/methods; Point Mutation/genetics; Sequence Analysis, DNA/methods; DNA Mutational Analysis; DNA Probes/chemistry; Fluorescence; Genes, ras/genetics; Genetic Testing; Heterozygote; Humans; Neoplasms/genetics

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Collection: 01-internacional Database: MEDLINE Main subject: Sequence Analysis, DNA / Point Mutation / Exodeoxyribonucleases / Nucleic Acid Hybridization Type of study: Diagnostic_studies / Prognostic_studies Limits: Humans Language: En Journal: Biochim Biophys Acta Year: 1998 Type: Article Affiliation country: Netherlands

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