Co-variables influencing 5-fluorouracil clearance during continuous venous infusion. A NONMEM analysis.

Etienne, M C; Chatelut, E; Pivot, X; Lavit, M; Pujol, A; Canal, P; Milano, G

Etienne, M C; Chatelut, E; Pivot, X; Lavit, M; Pujol, A; Canal, P; Milano, G.

Affiliation

Etienne MC; Oncopharmacology Laboratory, Centre Antoine Lacassagne, Toulouse, France.

Eur J Cancer ; 34(1): 92-7, 1998 Jan.

Article in En | MEDLINE | ID: mdl-9624244

Subject(s)

Antimetabolites, Antineoplastic/pharmacokinetics; Fluorouracil/pharmacokinetics; Neoplasms/metabolism; Adult; Age Factors; Aged; Aged, 80 and over; Body Surface Area; Dihydrouracil Dehydrogenase (NADP); Esophageal Neoplasms/drug therapy; Esophageal Neoplasms/metabolism; Female; Head and Neck Neoplasms/drug therapy; Head and Neck Neoplasms/metabolism; Humans; Infusions, Intravenous; Liver Function Tests; Male; Middle Aged; Neoplasms/drug therapy; Oxidoreductases/metabolism; Sex Factors; Time Factors

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Collection: 01-internacional Database: MEDLINE Main subject: Fluorouracil / Neoplasms / Antimetabolites, Antineoplastic Type of study: Prognostic_studies Limits: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Language: En Journal: Eur J Cancer Year: 1998 Type: Article Affiliation country: France

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