Lack of specific association of presenilin 1 (PS-1) protein with plaques and tangles in Alzheimer's disease.

Xia, M Q; Berezovska, O; Kim, T W; Xia, W M; Liao, A; Tanzi, R E; Selkoe, D; Hyman, B T

Xia, M Q; Berezovska, O; Kim, T W; Xia, W M; Liao, A; Tanzi, R E; Selkoe, D; Hyman, B T.

Affiliation

Xia MQ; Alzheimer's Research Unit, Department of Neurology, Massachusetts General Hospital-East, Charlestown 02129, USA.

J Neurol Sci ; 158(1): 15-23, 1998 Jun 11.

Article in En | MEDLINE | ID: mdl-9667772

Subject(s)

Alzheimer Disease/metabolism; Brain Chemistry; Membrane Proteins/analysis; Nerve Tissue Proteins/analysis; Neurofibrillary Tangles/chemistry; Plaque, Amyloid/chemistry; Alzheimer Disease/genetics; Alzheimer Disease/pathology; Animals; Antibodies, Monoclonal/immunology; Astrocytoma/pathology; Blotting, Western; CHO Cells; Cricetinae; Cricetulus; Flow Cytometry; Fluorescent Antibody Technique, Indirect; Glioma/pathology; Humans; Leukemia, Monocytic, Acute/pathology; Microglia/chemistry; Neurocytoma/pathology; Neurons/chemistry; Presenilin-1; Recombinant Fusion Proteins/analysis; Transfection; Tumor Cells, Cultured

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Collection: 01-internacional Database: MEDLINE Main subject: Brain Chemistry / Neurofibrillary Tangles / Plaque, Amyloid / Alzheimer Disease / Membrane Proteins / Nerve Tissue Proteins Type of study: Risk_factors_studies Limits: Animals / Humans Language: En Journal: J Neurol Sci Year: 1998 Type: Article Affiliation country: United States

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