Sulindac sulfide inhibits Ras signaling.

Herrmann, C; Block, C; Geisen, C; Haas, K; Weber, C; Winde, G; Möröy, T; Müller, O

Herrmann, C; Block, C; Geisen, C; Haas, K; Weber, C; Winde, G; Möröy, T; Müller, O.

Affiliation

Herrmann C; Max-Planck-Institut für molekulare Physiologie, Abteilung für Strukturelle Biologie, Dortmund, Germany.

Oncogene ; 17(14): 1769-76, 1998 Oct 08.

Article in En | MEDLINE | ID: mdl-9778042

Subject(s)

Antineoplastic Agents/pharmacology; Oncogene Protein p21(ras)/metabolism; Signal Transduction/drug effects; Sulindac/analogs & derivatives; 3T3 Cells; Animals; Antineoplastic Agents/metabolism; Cell Transformation, Neoplastic/drug effects; Cells, Cultured; Humans; Mice; Oncogene Protein p21(ras)/genetics; Proto-Oncogene Proteins c-raf/antagonists & inhibitors; Rats; Sulindac/metabolism; Sulindac/pharmacology; Transcriptional Activation

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Collection: 01-internacional Database: MEDLINE Main subject: Signal Transduction / Oncogene Protein p21(ras) / Sulindac / Antineoplastic Agents Limits: Animals / Humans Language: En Journal: Oncogene Journal subject: BIOLOGIA MOLECULAR / NEOPLASIAS Year: 1998 Type: Article Affiliation country: Germany

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