Monoclonal autoantibodies specific for oxidized phospholipids or oxidized phospholipid-protein adducts inhibit macrophage uptake of oxidized low-density lipoproteins.

Hörkkö, S; Bird, D A; Miller, E; Itabe, H; Leitinger, N; Subbanagounder, G; Berliner, J A; Friedman, P; Dennis, E A; Curtiss, L K; Palinski, W; Witztum, J L

Hörkkö, S; Bird, D A; Miller, E; Itabe, H; Leitinger, N; Subbanagounder, G; Berliner, J A; Friedman, P; Dennis, E A; Curtiss, L K; Palinski, W; Witztum, J L.

Affiliation

Hörkkö S; Department of Medicine, University of California, San Diego, La Jolla, California 92093-0682, USA.shorkko@ucsd.edu

J Clin Invest ; 103(1): 117-28, 1999 Jan.

Article in En | MEDLINE | ID: mdl-9884341

Subject(s)

Antibodies, Monoclonal/immunology; Lipoproteins, LDL/immunology; Macrophages, Peritoneal/metabolism; Animals; Antibodies, Monoclonal/metabolism; Apolipoproteins E/deficiency; Apolipoproteins E/genetics; Autoantibodies/immunology; Autoantibodies/metabolism; Copper/pharmacology; Emulsions/metabolism; Epitopes/immunology; Immunoglobulin Fab Fragments/immunology; Immunoglobulin Fab Fragments/metabolism; Lipid Peroxides/immunology; Lipoproteins, LDL/metabolism; Liposomes/immunology; Liposomes/metabolism; Mice; Phospholipids/immunology; Protein Binding

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Macrophages, Peritoneal / Lipoproteins, LDL / Antibodies, Monoclonal Limits: Animals Language: En Journal: J Clin Invest Year: 1999 Type: Article

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