Bioactivities of extracts from the marine sponge Halichondria panicea
J. venom. anim. toxins incl. trop. dis
; 15(3): 444-459, 2009. ilus, tab
Article
en En
| LILACS, VETINDEX
| ID: lil-525813
Biblioteca responsable:
BR68.1
ABSTRACT
In the present study, we screened the biological activity of extracts from the marine sponge Halichondria panicea collected in the Arabian Sea. Crude toxin was obtained by methanol, chloroform-methanol (21) and aqueous extraction. Subsequently, the protein concentration of each crude extract was determined. The impact of both sponge methanolic and aqueous extracts was found to increase activities of Na+-K+ ATP-ase and Mg++ ATP-ase. In the case of chloroform-methanol extract, higher concentrations increased acetylcholine esterase (AchE) activity. The methanolic and chloroform-methanol extracts exhibited hemolytic activity on chicken and human erythrocytes, whereas the aqueous extract failed to do so. Methanol and aqueous extracts produced an immunostimulating effect and all extracts revealed angiogenic activity. The aqueous extract yielded nine bands by SDS-PAGE on 12% gel.(AU)
Palabras clave
Texto completo:
1
Colección:
01-internacional
Banco de datos:
LILACS
/
VETINDEX
Asunto principal:
Poríferos
/
Productos Biológicos
/
Ambiente Marino
/
Adenosina Trifosfato
/
Electroforesis en Gel de Poliacrilamida
Límite:
Animals
Idioma:
En
Revista:
J. venom. anim. toxins incl. trop. dis
Asunto de la revista:
TOXICOLOGIA
Año:
2009
Tipo del documento:
Article
País de afiliación:
India