Cerebral aneurysm rupture after r-TPA thrombolysis for acute myocardial infarction.
Surg Neurol
; 52(6): 623-6, 1999 Dec.
Article
en En
| MEDLINE
| ID: mdl-10660031
ABSTRACT
BACKGROUND:
Intracranial hemorrhage is the most dreaded risk of thrombolytic therapy for acute myocardial infarction because of the high mortality and disability rates associated with this complication. Brain structural lesions may predispose a patient to bleeding. To date, aneurysm rupture has not been described as a complication of such therapy. CASE DESCRIPTION A 66-year-old hypertensive woman was admitted because of chest pain. Myocardial infarction was diagnosed and fibrinolytic therapy with recombinant tissue plasminogen activator (r-TPA) was initiated. Eight hours after admission she became unconscious. Brain computed tomography scan showed subarachnoid hemorrhage, and a cerebral arteriography showed an anterior communicating artery aneurysm. Because of her poor clinical condition treatment was postponed. Death occurred 7 days later because of multiorgan failure.CONCLUSIONS:
Cerebral aneurysms should be considered as a possible contributing factor to intracranial bleeding after thrombolytic therapy.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Terapia Trombolítica
/
Aneurisma Intracraneal
/
Activador de Tejido Plasminógeno
/
Aneurisma Roto
/
Infarto del Miocardio
Tipo de estudio:
Etiology_studies
/
Risk_factors_studies
Límite:
Aged
/
Female
/
Humans
Idioma:
En
Revista:
Surg Neurol
Año:
1999
Tipo del documento:
Article
País de afiliación:
España