Plasma L-tryptophan depletion and aggression.
Adv Exp Med Biol
; 467: 57-65, 1999.
Article
en En
| MEDLINE
| ID: mdl-10721038
ABSTRACT
There is a well-established relationship between aggression and lowered serotonin neuro-transmission. Recently developed methodologies for manipulating L-tryptophan levels (and brain serotonin) have been applied to human laboratory studies of aggression. Collectively, these studies provide further evidence for the serotonin-aggression relationship. Two important findings have been made recently (1) subsets of individuals (e.g., persons self-rating high on aggressive or hostility scales) may differ in their susceptibility to aggression produced through plasma tryptophan depletion; and (2) alcohol in combination with L-tryptophan depletion has an additive effect on aggression. All previous studies have been conducted with men. Extending these studies to women appears to be the much-needed next step given that serotonergic levels appear to vary both as a function of the menstrual cycle phase and menstrual symptomatology.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Triptófano
/
Encéfalo
/
Serotonina
/
Agresión
Límite:
Animals
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Adv Exp Med Biol
Año:
1999
Tipo del documento:
Article
País de afiliación:
Estados Unidos