Protected polymorphism in the two-locus haploid model with unpredictable fitnesses.
J Math Biol
; 40(3): 251-77, 2000 Mar.
Article
en En
| MEDLINE
| ID: mdl-10794437
ABSTRACT
In an unpredictable environment, the distributions of alleles from which polymorphism can be maintained forever belong to a certain set, the C-viability kernel. Such a set is calculated in the two-locus haploid model, as well as the corresponding fitnesses at any time which make this maintenance possible. The dependence of the C-viability kernel on the set U of admissible fitnesses and on the recombination rate r is studied. Notably, the C-viability kernel varies rapidly in the neighborhood of equal fitness of AB and ab; it becomes empty when ab has a fitness below a certain function, which is delineated, of the recombination rate. The properties of the two-locus model under constraints, out of equilibrium and with unpredictable selection are thus presented.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Polimorfismo Genético
/
Simulación por Computador
/
Haplotipos
/
Modelos Genéticos
Límite:
Animals
/
Humans
Idioma:
En
Revista:
J Math Biol
Año:
2000
Tipo del documento:
Article
País de afiliación:
Francia