Human memory formation is accompanied by rhinal-hippocampal coupling and decoupling.
Nat Neurosci
; 4(12): 1259-64, 2001 Dec.
Article
en En
| MEDLINE
| ID: mdl-11694886
ABSTRACT
In humans, distinct processes within the hippocampus and rhinal cortex support declarative memory formation. But do these medial temporal lobe (MTL) substructures directly cooperate in encoding new memories? Phase synchronization of gamma-band electroencephalogram (EEG) oscillations (around 40 Hz) is a general mechanism of transiently connecting neural assemblies. We recorded depth-EEG from within the MTL of epilepsy patients performing a memorization task. Successful as opposed to unsuccessful memory formation was accompanied by an initial elevation of rhinal-hippocampal gamma synchronization followed by a later desynchronization, suggesting that effective declarative memory formation is accompanied by a direct and temporarily limited cooperation between both MTL substructures.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Relojes Biológicos
/
Corteza Entorrinal
/
Sincronización Cortical
/
Hipocampo
/
Memoria
/
Vías Nerviosas
/
Neuronas
Tipo de estudio:
Etiology_studies
Límite:
Adult
/
Female
/
Humans
/
Male
Idioma:
En
Revista:
Nat Neurosci
Asunto de la revista:
NEUROLOGIA
Año:
2001
Tipo del documento:
Article
País de afiliación:
Alemania