Characterization of cardiac muscle factor 1 sequence motifs: retinoblastoma protein binding and nuclear localization.
Gene
; 282(1-2): 53-64, 2002 Jan 09.
Article
en En
| MEDLINE
| ID: mdl-11814677
ABSTRACT
Cardiac muscle factor 1 (CMF1) is characterized as a protein important in cardiac and skeletal myocyte differentiation and is expressed in a developmentally regulated manner. Sequence analysis data showed that CMF1 has crucial protein-protein interaction domains, has a retinoblastoma protein-binding site which interacts with RB directly in vitro and in the embryo, has a functional nuclear localization signal and is highly homologous to other cell cycle regulatory proteins such as mitosin and centromere protein F, which suggests that CMF1 may be involved in regulating the cell cycle.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Aviares
/
Proteínas Musculares
Límite:
Animals
Idioma:
En
Revista:
Gene
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos