Rhino-orbital and rhino-orbito-cerebral mucormycosis.
Otolaryngol Head Neck Surg
; 127(1): 22-31, 2002 Jul.
Article
en En
| MEDLINE
| ID: mdl-12161726
ABSTRACT
BACKGROUND:
Rhino-orbito-cerebral mucormycosis (ROCM) is a devastating infection of immunocompromised hosts. We present our experience with 19 ROCM cases and attempt to define preferred diagnostic and treatment protocols.METHODS:
All had tissue biopsies obtained studied by direct smear, histologic studies, and cultures. Imaging was obtained in 14 cases.RESULTS:
Sixteen patients presented between August and November. Six had mixed fungal infections. Seven patients had end-stage underlying disease or infection and did not undergo surgery and 4 had an indolent form of disease. Patients were treated by surgery and by amphotericin B. The overall survival was 47%.CONCLUSIONS:
ROCM may have seasonal incidence peaking in the fall and early winter. The therapeutic approach should be unchanged in cases of mixed fungal infections. Amphotericin B with aggressive debridement remains the mainstay of treatment. Early recognition and treatment are essential. A presentation and survival-dependent classification of ROCM are offered.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Infecciones Oportunistas
/
Infecciones Fúngicas del Ojo
/
Enfermedades Nasales
/
Meningitis Fúngica
/
Mucormicosis
Tipo de estudio:
Etiology_studies
/
Guideline
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
En
Revista:
Otolaryngol Head Neck Surg
Año:
2002
Tipo del documento:
Article
País de afiliación:
Israel