[A patient with diffuse peritoneal metastases of GIST who was administered STI571].
Gan To Kagaku Ryoho
; 29(12): 2329-32, 2002 Nov.
Article
en Ja
| MEDLINE
| ID: mdl-12484066
ABSTRACT
We report a patient with diffuse peritoneal metastases of GIST who was administered STI571 (a tyrosine kinase inhibitor). She was a 45-year-old woman who underwent surgery for a mass that was suspected to be an ovarian tumor. The postoperative diagnosis was GIST developing from the small intestine. Two years later, multiple peritoneal metastases were noted and a complete macroscopic resection was done. Six months after the second operation, she needed a third operation and complete macroscopic resection was repeated. Only 4 months after the third operation, she underwent a fourth operation. We resected massive peritoneal metastases, but diffuse metastases remained. Therefore, we started to administer STI571 at 400 mg/day. She has been free from peritoneal masses for 9 months after the fourth operation. We recommend STI571 for uncontrolled diffuse peritoneal metastases of GIST.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Peritoneales
/
Piperazinas
/
Pirimidinas
/
Inhibidores Enzimáticos
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Neoplasias Gastrointestinales
/
Antineoplásicos
Límite:
Female
/
Humans
/
Middle aged
Idioma:
Ja
Revista:
Gan To Kagaku Ryoho
Año:
2002
Tipo del documento:
Article