Glycosylation and lectins-examples of immunesurveillance and immune evasion.
Histol Histopathol
; 19(2): 527-33, 2004 04.
Article
en En
| MEDLINE
| ID: mdl-15024714
ABSTRACT
Cell surface proteins are posttranslationally modified by tightly regulated enzymes of glycosylation. Typical patterns of glycosylation may signal pathological situations to the immune system. Here, carbohydrate receptors on the surface of cells in the immune system are involved in regulation of effector cells. Moreover, some lectins are circulating in the plasma and take part in host defense. The code of carbohydrate modifications is impaired in malignant cells and yet they are not eliminated. In this review, we focus on recent experimental evidence for regulatory functions of lectins and carbohydrate derivatives in the immune system and tumours.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Sistema Inmunológico
/
Lectinas
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Histol Histopathol
Asunto de la revista:
HISTOLOGIA
/
PATOLOGIA
Año:
2004
Tipo del documento:
Article
País de afiliación:
Alemania