Determinants of airway response to challenge with distilled water in a population sample of children aged 7 to 10 years old.
Chest
; 102(3): 764-70, 1992 Sep.
Article
en En
| MEDLINE
| ID: mdl-1516399
ABSTRACT
We challenged 446 schoolchildren and measured the percent decrease in FEV1 following 10 min of tidal inhalation of UNDW. Assessment tools for respiratory symptoms and atopy were questionnaire and skin testing, respectively. A previous diagnosis of asthma was most strongly associated with a positive airway response (defined as a fall in FEV1 greater than or equal to 10 percent. A positive response was also associated with atopy, presence of cough, cough during night, or any respiratory symptom. A child's age and the prechallenge FEF75% also explained response to distilled water indicating less responsiveness for older children and those with relative greater airway diameter. For the previous diagnosis of asthma, a positive distilled water challenge test had a sensitivity of 36 percent and a specificity of 92 percent. We conclude that a significant relationship between airway response to distilled water, asthma and symptoms suggestive for asthma exists for a childhood population sample.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Asma
/
Pruebas de Provocación Bronquial
/
Agua
Tipo de estudio:
Diagnostic_studies
/
Prevalence_studies
/
Prognostic_studies
/
Risk_factors_studies
Límite:
Child
/
Female
/
Humans
/
Male
País/Región como asunto:
Europa
Idioma:
En
Revista:
Chest
Año:
1992
Tipo del documento:
Article
País de afiliación:
Austria