Molecular basis of quinolone resistance in Escherichia coli from wild birds.
Can J Vet Res
; 68(3): 229-31, 2004 Jul.
Article
en En
| MEDLINE
| ID: mdl-15352551
ABSTRACT
Nine quinolone resistant (minimal inhibitory concentration [MIC] was > 32 microg/mL for nalidixic acid, > 1 microg/mL for ciprofloxacin) isolates of Escherichia coli have been found in wild birds with septicemia. All of the isolates were aerobactin positive. The mechanisms of resistance were characterised by sequencing the quinolone resistance-determining region (QRDR) of the gyrA, gyrB, parC, and parE genes. Sequence analysis of the gyrA gene in all isolates identified only 1 nucleotide substitution at codon Serine-83 for Leucine-83. Sequence analysis of the gyrB, parC, and parE QRDR genes revealed no mutations in any of the isolates. This study was conducted to determine the importance of these genes in the susceptibility of E. coli strains isolated from wild birds to quinolones.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Enfermedades de las Aves
/
Fluoroquinolonas
/
Farmacorresistencia Bacteriana
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Escherichia coli
/
Genes Bacterianos
/
Antiinfecciosos
Límite:
Animals
Idioma:
En
Revista:
Can J Vet Res
Asunto de la revista:
MEDICINA VETERINARIA
Año:
2004
Tipo del documento:
Article
País de afiliación:
España