A maternal warm-reactive autoantibody presenting as a positive direct antiglobulin test in a neonate.
Immunohematology
; 13(1): 6-8, 1997.
Article
en En
| MEDLINE
| ID: mdl-15387790
ABSTRACT
Autoimmune hemolytic anemia in pregnancy is a rare cause of hemolytic disease of the newborn. This report describes a neonate with a mild hemolytic process and a positive direct antiglobulin test (DAT) presenting as the first manifestations of a maternal warm-reactive autoantibody. A full-term male neonate, blood group O, had a strongly positive DAT and laboratory evidence suggestive of a mild hemolytic process. The neonate's mother was also group O and had a negative antibody screen. Umbilical cord blood testing revealed a panreactive eluate though the antibody was not detected in cord serum. The neonate's mother was also found to have a positive DAT. A panagglutinin was identified in an eluate of her red cells, although the autoantibody could not be detected in her serum by a variety of sensitive techniques. There was no clinical or laboratory evidence of maternal hemolysis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Immunohematology
Asunto de la revista:
ALERGIA E IMUNOLOGIA
/
HEMATOLOGIA
Año:
1997
Tipo del documento:
Article
País de afiliación:
Estados Unidos