Reduction of beta-hydroxyketones by SmI2/H2O/Et3N.
Org Lett
; 7(1): 119-22, 2005 Jan 06.
Article
en En
| MEDLINE
| ID: mdl-15624992
ABSTRACT
Reduction of a series of beta-hydroxyketones by SmI2/H2O/Et3N provided 1,3-diols in quantitative yields. The reactions were exceedingly clean with no byproduct formation, negating the need for further purification. Most reactions provided moderate to excellent diastereoselectivity with syn-diols as the major isomer in most instances.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2005
Tipo del documento:
Article
País de afiliación:
Estados Unidos