[Relationship between phlegm-stasis syndrome and fibrinolytic status in patients with non-alcoholic fatty liver].
Zhongguo Zhong Xi Yi Jie He Za Zhi
; 25(1): 22-4, 2005 Jan.
Article
en Zh
| MEDLINE
| ID: mdl-15719744
ABSTRACT
OBJECTIVE:
To explore the relationship between phlegm-stasis syndrome (PSS) and the fibrinolytic status in patients with non-alcoholic fatty liver (NAFL).METHODS:
Seventy patients with NAFL were divided into the PSS group and non-PSS group according to TCM Syndrome typing, and a control group consisted of 28 healthy subjects was set up. Levels of plasminogen (PLG), tissue plasminogen activator (t-PA), plasminogen activator inhibitor-1 (PAI-1) and D-dimer were determined and compared.RESULTS:
The activity of t-PA in NAFL patients was significantly lower than that in the control group (P<0.05), and PLG and PAI-1 were significantly higher than those in the control group (P<0.05). In respect to the TCM Syndrome typing, in patients of PSS, t-PA was significantly lower and PLG, PAI-1 were significantly higher than those in patients of non-PSS (P<0.05 or P<0.01), while D-dimer was insignificantly different between patients of the two Syndrome types (P>0.05).CONCLUSION:
NAFL patients of PSS type shows significant lower of fibrinolytic activity, indicating that there is certain degree of microcirculatory disturbance and hyper viscosity state, so the application of dissolving phlegm and dispelling stasis principle in treating NAFL is significant.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Plasminógeno
/
Activador de Tejido Plasminógeno
/
Inhibidor 1 de Activador Plasminogénico
/
Hígado Graso
/
Fibrinólisis
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Idioma:
Zh
Revista:
Zhongguo Zhong Xi Yi Jie He Za Zhi
Asunto de la revista:
TERAPIAS COMPLEMENTARES
Año:
2005
Tipo del documento:
Article