Leiomyosarcomatous transformation of unknown pediatric primary brainstem lesion following radiotherapy. Case report.
Neurosurg Focus
; 12(6): ecp2, 2002 Jun 15.
Article
en En
| MEDLINE
| ID: mdl-15926790
ABSTRACT
Primary leiomyosarcoma of the central nervous system is rare and has been described both de novo and following temporally remote radiotherapy for a different unrelated malignancy. The authors report the case of a 42-year-old man in whom 60Co radiation treatment had been performed for an unknown primary mass in the brainstem 25 years previously. He presented with progressive neurological deterioration after undergoing many years of conservative therapy. A stereotactic biopsy sampling procedure was performed, and examination of the left cerebral pedunculopontine lesion revealed a spindle cell neoplasm. Histopathological and immunohistochemical examination of the tumor obtained from definitive resection suggested leiomyosarcomatous transformation of ganglioglioma.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Neoplasias Encefálicas
/
Transformación Celular Neoplásica
/
Ganglioglioma
/
Leiomiosarcoma
/
Neoplasias Inducidas por Radiación
Tipo de estudio:
Diagnostic_studies
Límite:
Adolescent
/
Humans
/
Male
Idioma:
En
Revista:
Neurosurg Focus
Asunto de la revista:
NEUROCIRURGIA
Año:
2002
Tipo del documento:
Article
País de afiliación:
Estados Unidos