Cortical motor activation patterns following hand transplantation and replantation.
J Hand Surg Br
; 30(5): 530-3, 2005 Oct.
Article
en En
| MEDLINE
| ID: mdl-16055246
ABSTRACT
We studied cortical activation patterns by functional MRI in a patient who received bilateral hand transplantation after amputation 6 years ago and in a patient who had received unilateral hand replantation within 2 hours after amputation. In the early postoperative period, the patient who had had the hand transplantation revealed strong activation of a higher motor area, only weak activation of the primary sensorimotor motor cortex and no activation of the primary somatosensory cortex. At 1-year follow-up, a small increase in primary sensorimotor motor cortex activation was observed. Activation of the primary somatosensory cortex was only seen at the 2 year follow-up. By contrast, after hand replantation, the activation pattern was similar to that of the uninjured hand within 6 weeks. This included activation of the primary sensorimotor motor cortex, higher motor areas and primary somatosensory cortex. Transplantation after long-standing amputation results in cortical reorganization occurring over a 2-year period. In contrast, hand replantation within a few hours preserves a normal activation pattern.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Reimplantación
/
Mano
/
Corteza Motora
Límite:
Adult
/
Female
/
Humans
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Male
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Middle aged
Idioma:
En
Revista:
J Hand Surg Br
Año:
2005
Tipo del documento:
Article
País de afiliación:
Austria