[Pathomorphology and morphogenesis of myocarditis in typhoid fever].

ABSTRACT

Archives specimens of the heart, autopsy protocols and disease histories of 16 soldiers and officers of Soviet army who died in Afghanistan of typhoid fever were studied. It is concluded on the basis of morphology and statistics that interstitial myocarditis and sometimes pancarditis develop on the 2nd week of the basic disease. Characteristic features of typhoid fever myocarditis are inflammation of the heart intramural vessels, microcirculatory disturbances, edema and lymphocytic-macrophogeal infiltration of the stroma, sometimes with formation of granulomas, dystrophic and necrotic changes of cardiomyocytes.