Synovial sarcoma with radiological appearances of primitive neuroectodermal tumour/Ewing sarcoma: differentiation by molecular genetic studies.
Skeletal Radiol
; 35(4): 233-9, 2006 Apr.
Article
en En
| MEDLINE
| ID: mdl-16220269
ABSTRACT
Synovial sarcoma (SS) arises in soft tissues but may invade adjacent bone. We describe a case of SS presenting as aggressive lysis of the proximal ulna, the imaging of which suggested a primary bone lesion. Needle biopsy showed a "small round blue cell tumour", and a primitive neuroectodermal tumour (PNET)/Ewing sarcoma was suggested on the basis of the imaging appearances. The definitive diagnosis of synovial sarcoma was made following molecular genetic studies, which demonstrated a fusion product incorporating the genes SYT and SSX1. The importance of correct diagnosis to guide appropriate management, and, therefore, the necessity for molecular genetic studies, is discussed.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Cúbito
/
Neoplasias Óseas
/
Tumores Neuroectodérmicos Primitivos
/
Sarcoma Sinovial
Tipo de estudio:
Diagnostic_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
Skeletal Radiol
Año:
2006
Tipo del documento:
Article
País de afiliación:
Reino Unido