[Inter-laboratory validation studies of biological method for determination of tetracyclines in royal jelly].
Shokuhin Eiseigaku Zasshi
; 46(6): 286-9, 2005 Dec.
Article
en Ja
| MEDLINE
| ID: mdl-16440791
ABSTRACT
Inter-laboratory validation studies were conducted in 5 laboratories to validate the biological method for determination of tetracyclines in royal jelly. Oxytetracycline spiked at the levels of 0.2 and 1.0 ppm was analyzed. Mean recoveries were 88 and 90%, reproducibility relative standard deviations (RSD(R)) were 13.7 and 7.8%, and HORRAT(R) values were 0.7 and 0.5. Samples containing residues at the levels of 0.25 and 0.80 ppm were analyzed. Mean recoveries were 73 and 77%, RSD(R) were 12.6 and 10.5%, and HORRAT(R) values were 0.6 and 0.6. The determination limit was 0.1 ppm (oxytetracycline, tetracycline) and 0.02 ppm (chlortetracycline). These results show that this method has good performance.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tetraciclinas
/
Bioensayo
/
Residuos de Medicamentos
/
Contaminación de Alimentos
/
Ácidos Grasos
/
Análisis de los Alimentos
/
Laboratorios
/
Antibacterianos
Tipo de estudio:
Clinical_trials
Idioma:
Ja
Revista:
Shokuhin Eiseigaku Zasshi
Año:
2005
Tipo del documento:
Article
País de afiliación:
Japón