[Lymph node tuberculosis as primary manifestation of Hodgkin's disease]. / Lymphknotentuberkulose als Erstmanifestation eines Morbus Hodgkin.
Med Klin (Munich)
; 101(6): 500-4, 2006 Jun 15.
Article
en De
| MEDLINE
| ID: mdl-16767573
HISTORY AND FINDINGS ON ADMISSION: A 63-year-old female patient was admitted to the authors' hospital for further diagnostic work-up for suspected reactivation of a previously successfully treated lymph node tuberculosis, which had been diagnosed 1 year prior to the current admission. The clinical signs consisted of worsening of the patient's general condition, negacervical lymphadenopathy, night sweats, dyspnea, and superficial inflammation of the right mamma. FINDINGS: A contrast-enhanced CT scan of the neck, thorax and abdomen revealed a generalized enlargement of the cervical, axillar, mediastinal and retroperitoneal lymph nodes, multiple intrapulmonary nodular lesions with a diameter of up to 6 mm, and a substantial right-sided pleural effusion. COURSE OF DISEASE: Under the assumption of reactivation of a lymph node tuberculosis, the patient was initially treated with an extended tuberculostatic therapy. Because of disease progression another lymph node biopsy was performed revealing Hodgkin's disease of mixed-cellularity type with a partly histiocytic necrotizing, partly tuberculoid reaction. The biopsy was negative for acid-fast bacilli. Thereupon initiated chemotherapy according to the ABVD protocol led to a rapid amelioration of the clinical symptoms. CONCLUSION: In the clinical setting of suspected or confirmed lymph node tuberculosis malignant lymphoma should always be considered. This consideration is particular important since Hodgkin's disease is typically associated with a cellular immunosuppression predisposing the subject to tuberculosis.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tuberculosis Ganglionar
/
Enfermedad de Hodgkin
/
Tuberculosis Resistente a Múltiples Medicamentos
Tipo de estudio:
Diagnostic_studies
/
Guideline
Límite:
Humans
Idioma:
De
Revista:
Med Klin (Munich)
Año:
2006
Tipo del documento:
Article