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[Lymph node tuberculosis as primary manifestation of Hodgkin's disease]. / Lymphknotentuberkulose als Erstmanifestation eines Morbus Hodgkin.
Audebert, Franz; Schneidewind, Arne; Hartmann, Pia; Kullmann, Frank; Schölmerich, Jürgen.
Afiliación
  • Audebert F; Klinik und Poliklinik für Innere Medizin I, Universität Regensburg, 93042 Regensburg. franz.audebert@klinik.uni-r.de
Med Klin (Munich) ; 101(6): 500-4, 2006 Jun 15.
Article en De | MEDLINE | ID: mdl-16767573
HISTORY AND FINDINGS ON ADMISSION: A 63-year-old female patient was admitted to the authors' hospital for further diagnostic work-up for suspected reactivation of a previously successfully treated lymph node tuberculosis, which had been diagnosed 1 year prior to the current admission. The clinical signs consisted of worsening of the patient's general condition, negacervical lymphadenopathy, night sweats, dyspnea, and superficial inflammation of the right mamma. FINDINGS: A contrast-enhanced CT scan of the neck, thorax and abdomen revealed a generalized enlargement of the cervical, axillar, mediastinal and retroperitoneal lymph nodes, multiple intrapulmonary nodular lesions with a diameter of up to 6 mm, and a substantial right-sided pleural effusion. COURSE OF DISEASE: Under the assumption of reactivation of a lymph node tuberculosis, the patient was initially treated with an extended tuberculostatic therapy. Because of disease progression another lymph node biopsy was performed revealing Hodgkin's disease of mixed-cellularity type with a partly histiocytic necrotizing, partly tuberculoid reaction. The biopsy was negative for acid-fast bacilli. Thereupon initiated chemotherapy according to the ABVD protocol led to a rapid amelioration of the clinical symptoms. CONCLUSION: In the clinical setting of suspected or confirmed lymph node tuberculosis malignant lymphoma should always be considered. This consideration is particular important since Hodgkin's disease is typically associated with a cellular immunosuppression predisposing the subject to tuberculosis.
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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tuberculosis Ganglionar / Enfermedad de Hodgkin / Tuberculosis Resistente a Múltiples Medicamentos Tipo de estudio: Diagnostic_studies / Guideline Límite: Humans Idioma: De Revista: Med Klin (Munich) Año: 2006 Tipo del documento: Article
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Colección: 01-internacional Banco de datos: MEDLINE Asunto principal: Tuberculosis Ganglionar / Enfermedad de Hodgkin / Tuberculosis Resistente a Múltiples Medicamentos Tipo de estudio: Diagnostic_studies / Guideline Límite: Humans Idioma: De Revista: Med Klin (Munich) Año: 2006 Tipo del documento: Article