jpHMM at GOBICS: a web server to detect genomic recombinations in HIV-1.
Nucleic Acids Res
; 34(Web Server issue): W463-5, 2006 Jul 01.
Article
en En
| MEDLINE
| ID: mdl-16845050
ABSTRACT
Detecting recombinations in the genome sequence of human immunodeficiency virus (HIV-1) is crucial for epidemiological studies and for vaccine development. Herein, we present a web server for subtyping and localization of phylogenetic breakpoints in HIV-1. Our software is based on a jumping profile Hidden Markov Model (jpHMM), a probabilistic generalization of the jumping-alignment approach proposed by Spang et al. The input data for our server is a partial or complete genome sequence from HIV-1; our tool assigns regions of the input sequence to known subtypes of HIV-1 and predicts phylogenetic breakpoints. jpHMM is available online at http//jphmm.gobics.de/.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Recombinación Genética
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Programas Informáticos
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VIH-1
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Genómica
Tipo de estudio:
Health_economic_evaluation
/
Prognostic_studies
Idioma:
En
Revista:
Nucleic Acids Res
Año:
2006
Tipo del documento:
Article
País de afiliación:
Alemania