Neonatal hypoxic-ischemic encephalopathy: multimodality imaging findings.
Radiographics
; 26 Suppl 1: S159-72, 2006 Oct.
Article
en En
| MEDLINE
| ID: mdl-17050513
ABSTRACT
Diffuse hypoxic-ischemic brain injury in the neonate results in neonatal hypoxic-ischemic encephalopathy (HIE). Because of differences in brain maturity at time of insult, severity of hypotension, and duration of insult, there are four distinct patterns of brain injury. Cranial ultra-sonography and computed tomography reveal periventricular leukomalacia, germinal matrix hemorrhage, and hydrocephalus. Magnetic resonance imaging is the most sensitive modality for evaluating the patterns of brain injury. In preterm neonates, mild hypotension causes periventricular injury; severe hypotension results in infarction of the deep gray matter, brainstem, and cerebellum. In term neonates, mild hypotension causes parasagittal cortical and subcortical injury; severe hypotension causes characteristic injury of the lateral thalami, posterior putamina, hippocampi, corticospinal tracts, and sensorimotor cortex. Prompt recognition of these imaging findings can help exclude other causes of encephalopathy, affect prognosis, and facilitate earlier (although mostly supportive) treatment.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Aumento de la Imagen
/
Técnica de Sustracción
/
Hipoxia-Isquemia Encefálica
Tipo de estudio:
Diagnostic_studies
/
Guideline
/
Prognostic_studies
Límite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
En
Revista:
Radiographics
Año:
2006
Tipo del documento:
Article
País de afiliación:
Estados Unidos