Ultrastructural localization of glycodelin oligosaccharides Le-x and Le-y in human seminal vesicles by immunogold staining.
J Anat
; 210(3): 352-6, 2007 Mar.
Article
en En
| MEDLINE
| ID: mdl-17331183
ABSTRACT
Histo-blood group antigens Le-x and Le-y are oligosaccharidic terminals that characterize many glycoproteins in the human tissues. In seminal plasma, they are expressed as part of the so-called glycodelin S, which is suggested to regulate sperm capacitation/decapacitation. It has recently been demonstrated that the core protein of glycodelin S is secreted by seminal vesicles. Here we show that epithelial cells of human seminal vesicles also release the Le-x and Le-y antigens. The presence of these substances in secretory material was revealed by means of an immunogold staining method in normal surgical samples. The results suggest that glycodelin S is secreted by seminal vesicles in its finished glycosylated form. Moreover, antigen reactivity was also revealed associated with plasma membranes.
Texto completo:
1
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Proteínas Gestacionales
/
Túbulos Seminíferos
/
Antígenos de Grupos Sanguíneos
/
Glicoproteínas
/
Antígenos del Grupo Sanguíneo de Lewis
Límite:
Humans
/
Male
Idioma:
En
Revista:
J Anat
Año:
2007
Tipo del documento:
Article
País de afiliación:
Italia