Photodynamic therapy for cutaneous verrucous carcinoma.
J Am Acad Dermatol
; 57(3): 516-9, 2007 Sep.
Article
en En
| MEDLINE
| ID: mdl-17434646
ABSTRACT
Cutaneous verrucous carcinoma is a low-grade and well-differentiated variant of squamous cell carcinoma. This rare neoplasm follows a seemingly indolent progression and exhibits a low metastatic potential. Photodynamic therapy relies on the selective intratumoral cell accumulation and photoactivation of a photosensitizer, leading to the generation of phototoxic compounds responsible for necrosis and apoptosis of the target cells. An 82-year-old man presenting with a large long-standing verrucous carcinoma on the leg was treated successfully by 6 photodynamic therapy sessions administered at weekly intervals using methyl-aminolevulinate and 57-J/cm(2) irradiations at 634-nm wavelength. The use of methyl-aminolevulinate-photodynamic therapy for treating cutaneous verrucous carcinoma had not been reported so far. It may represent a convenient therapeutic alternative in this setting.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Fotoquimioterapia
/
Neoplasias Cutáneas
/
Carcinoma Verrugoso
/
Dermatosis de la Pierna
Límite:
Aged80
/
Humans
/
Male
Idioma:
En
Revista:
J Am Acad Dermatol
Año:
2007
Tipo del documento:
Article
País de afiliación:
Bélgica