Laryngeal disorders in patients with gastroesophageal reflux disease.
Minerva Gastroenterol Dietol
; 53(2): 181-7, 2007 Jun.
Article
en En
| MEDLINE
| ID: mdl-17557046
ABSTRACT
Gastroesophageal reflux disease (GERD) is a common medical condition affecting approximately 35-40% of the adult population in the western world. Chronic laryngeal signs and symptoms associated with GERD are often referred to as reflux laryngitis or laryngopharyngeal reflux (LPR). It is estimated that up to 15% of all visits to the otolaryngology offices are because of manifestations of LPR. Injury may occur as a result of one or chronic reflux of gastroduodenal contents directly injuring the laryngeal mucosa. Since less amount of acid is required to make the injury to the larynx as compared to injury to esophagus; it is believed that intermittent exposure to small amount of gastric content can result in laryngitis. The most common presenting symptoms of LPR include hoarseness, sore throat, throat clearing, and chronic cough. The diagnosis of LPR is usually made on the basis of presenting symptoms and associated laryngeal signs including laryngeal edema and erythema. Current recommendation for management of this group of patients is empiric therapy with twice daily proton-pump inhibitors for 2 to 4 months. In majority of those who are unresponsive to such therapy other causes of laryngeal irritation is considered. Surgical fundoplication is most effective in those who are responsive to acid suppressive therapy.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Reflujo Gastroesofágico
/
Enfermedades de la Laringe
Tipo de estudio:
Guideline
Límite:
Humans
Idioma:
En
Revista:
Minerva Gastroenterol Dietol
Asunto de la revista:
CIENCIAS DA NUTRICAO
/
GASTROENTEROLOGIA
Año:
2007
Tipo del documento:
Article
País de afiliación:
Estados Unidos