Comparison of DNA replication in Xenopus laevis and Simian Virus 40.
Adv Exp Med Biol
; 604: 3-16, 2007.
Article
en En
| MEDLINE
| ID: mdl-17695718
ABSTRACT
DNA replication is a fundamental process within the cell cycle. The exact duplication of the genetic information ensures genome stability. Extensive research has identified the principal players required for the sequential processes origin-licensing (a controlled order of events giving a chromosome site the potential to be initiated within the S phase of the same cell cycle); initiation (by removing the license a previous licensed site is transformed into a site where the DNA helix starts to melt); and DNA replication (copying the parental DNA by leading and lagging strand DNA-synthesis). The present report compares the advantages and limitations of studying DNA replication in the model systems Xenopus laevis (X. laevis) and in Simian Virus 40 (SV40).
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Xenopus laevis
/
Virus 40 de los Simios
/
Replicación del ADN
Límite:
Animals
/
Humans
Idioma:
En
Revista:
Adv Exp Med Biol
Año:
2007
Tipo del documento:
Article
País de afiliación:
Irlanda