Integrating pathway data for systems pathology.
In Silico Biol
; 7(2 Suppl): S17-25, 2007.
Article
en En
| MEDLINE
| ID: mdl-17822386
ABSTRACT
The HumanPSD database on the complete proteomes of human, mouse and rat has been integrated with the databases TRANSFAC on gene regulation and TRANSPATH on signal transduction to provide a comprehensive systems biological platform for these organisms. As a next step, integration with PathoDB and PathoSign on pathologically relevant mutations is planned together with an extension beyond the limits of the individual cell, towards intercellular networks, by integrating the database EndoNet on hormonal networks as well. The overall aim is to come up with a platform that is suitable to provide knowledge for systems pathology, i. e. a system-wide modeling of pathological states and their development.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Bases de Datos Genéticas
/
Enfermedades Genéticas Congénitas
/
Mutación
Límite:
Animals
/
Humans
Idioma:
En
Revista:
In Silico Biol
Asunto de la revista:
BIOLOGIA MOLECULAR
Año:
2007
Tipo del documento:
Article
País de afiliación:
Alemania