Pilonidal sinus associated with cellular blue nevus. A previously unrecognized association.
J Cutan Pathol
; 34(12): 942-5, 2007 Dec.
Article
en En
| MEDLINE
| ID: mdl-18001419
ABSTRACT
A neoplasm associated with a pilonidal sinus (PS) is a rare occurrence in the course of a common disease. Early detection is imperative. To our knowledge, pilonidal disease associated with a cellular blue nevus (CBN) has not been reported. There is a 10% diagnostic error rate with this last lesion. Here we report the case of a 19-year-old man with recurrent sacrococcygeal PS infection associated with an indurated dome-shaped blue-black nodule 1.7 cm in diameter. Clinical diagnosis of the nodule was uncertain suggesting a pigmentary or a vascular tumor. A complete resection of the two lesions was achieved. Pathological study showed a CBN showing a predominantly alveolar pattern associated with a chronic pilonidal disease. The tumor cells showed diffuse strong reactivity for melan-A and HMB-45, and focal reactivity for S-100 protein. Staining for Ki-67 (MIB1) was virtually negative. Differential diagnoses included atypical CBN, borderline melanocytic tumor and malignant melanoma. Radical excision provides a good prognosis for the rare association consisting of a common disease such as PS with the uncommon CBN.
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Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Seno Pilonidal
/
Neoplasias Cutáneas
/
Nevo Azul
Tipo de estudio:
Diagnostic_studies
/
Prognostic_studies
/
Risk_factors_studies
/
Screening_studies
Límite:
Adult
/
Humans
/
Male
Idioma:
En
Revista:
J Cutan Pathol
Año:
2007
Tipo del documento:
Article
País de afiliación:
España