A luminescent sensor for tyrosine phosphorylation.
Org Lett
; 10(1): 5-8, 2008 Jan 03.
Article
en En
| MEDLINE
| ID: mdl-18069839
ABSTRACT
We have developed a luminogenic probe for tyrosine phosphorylation based on a short peptide sequence containing an iminodiacetate moiety near the site of phosphorylation. In response to kinase activity, the probe provides a strong luminescence enhancement, resulting from the increased ability of the probe to bind and sensitize Tb3+ and Eu3+ ions upon phosphorylation.
Buscar en Google
Colección:
01-internacional
Banco de datos:
MEDLINE
Asunto principal:
Tirosina
/
Elementos de la Serie de los Lantanoides
/
Luminiscencia
/
Mediciones Luminiscentes
Idioma:
En
Revista:
Org Lett
Asunto de la revista:
BIOQUIMICA
Año:
2008
Tipo del documento:
Article
País de afiliación:
Estados Unidos